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DBCO-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan deuterium-labeled-nitrogen 79 Purity (HPLC) >= 95%

SKU: 94571966879

4.4
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Description

79 Purity (HPLC) >= 95% Solubility DMSO

BI-3802 has antitumor activity

Product Name NDB-TM Synonyms CAS Number 871510-38-2 Related CAS Molecular Formula C10H10N4O3S Molecular Weight 266

6-isomer Synonyms: 6-Carboxytetramethylrhodamine

Trametinib (GSK1120212

DBCO-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan deuterium-labeled-nitrogen 79 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a DBCO Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to

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